St. Catherine Creek National Wildlife Refuge, encompassing 24,442 acres, with a potential size of 34,256 acres, is located in Adams County in southwest Mississippi. The headquarters lies ten miles south of Natchez. The western refuge boundary is formed by the Mississippi River. The eastern boundary meanders along the loessal bluffs and the southern boundary is the Homochitto River. Habitat on the refuge offers a myriad of ecological niches for wildlife. Cypress swamps and hardwood forests vegetated with oak, gum, elm, ash, cottonwood and pine comprise thirty percent of the refuge. Ten percent of the acreage is open water, while the remaining property consists of cleared land and batture land. The refuge is open to the public year-round. Available activities include fishing, hunting, bird watching and hiking. A three-mile nature trail is located near the headquarters where visitors can enjoy a peaceful opportunity to view wildlife. Refuge headquarters are open 7:30 a.m. until 4 p.m. Monday - Friday. They are closed all Federal holidays. Refuge hours are sunup to sundown.